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Issue Date: 11th July 2008

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.Optical sensor technology from Stratophase offers sensitive refractive index measurements even in volatile environments

A new sensor chip technology from university spinout Stratophase is offering pharmaceutical manufacturers a cost effective inline option for multipoint refractive index measurements of liquids, even in volatile environments.

With precision better than one part per million, the Stratophase sensors are capable of detecting even the most minute changes in the chemical composition of liquids. The robust, self-referenced sensor chips are suitable for use in any liquid processing application.

Because the SpectroSens sensor unit uses optical signals it does not need to be powered, and is therefore fundamentally safe for use in flammable environments, making it a cost-effective option for use in hazardous areas or with combustible chemicals.

Perfectly suited to use in laboratories and for point testing in the factory, multiple sensors can also be networked over large areas to a single readout unit, offering economical multipoint measurements.

Pharmaceutical manufacturers are moving away from end-of-line quality checks to in-line quality assurance in response to the new Food and Drug Administration (FDA) Process Analytical Technology [PAT] initiative. The flexible configuration possibilities, the elimination of batch testing and the real-time process information offered by the Stratophase technology make it a versatile and attractive solution for this application.

The ability to make multiwavelength measurements at a single point also offers the potential to compositionally ‘fingerprint’ liquids, further increasing the depth of information available to the user.

Stratophase has developed the SpectroSens technology based on proven science from the telecoms, optics and biotech sectors. The technology also has applications in industrial processes, life sciences R&D and food and drink manufacturing.

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